List of Spider-Man enemies

Spider-Man is a fictional superhero in the Marvel Universe debuting in the anthology comic book series issue Amazing Fantasy #15 (August 1962) in the Silver Age of Comics published by Marvel Comics. After his debut he would get his own comic book entitled The Amazing Spider-Man. The comic book series would introduce many of what would become his major supervillain adversaries. Spider-Man would then be popular enough for more Spider-Man comic spinoffs (The Spectacular Spider-Man, Marvel Team-Up, Web of Spider-Man, Peter Parker: Spider-Man etc.) which potentially introduced more recurring enemies of the web-slinger.

As with Spider-Man, the theme behind the villains' powers originate with scientific accidents or the misuse of scientific technology and also tend to have animal-themed costumes or powers (Vulture, Doctor Octopus, Lizard, Rhino, Scorpion, Jackal and Black Cat). There also consists supervillains with the powers over the elements (Sandman, Electro, Molten Man and Hydro-Man), some that are horror-themed (the Goblins, Morbius, the Symbiotes and Morlun) and some that are crime lords (Kingpin, Hammerhead and Silvermane). His rogue also consisted of some that are masters of trickery and deception such as the Chameleon and Mysterio. These villains oftentimes form teams such as the Sinister Six and the Sinister Syndicate to oppose the superhero.