Linda Buck
| Linda Buck | |
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Linda Buck attending 2004 Golden Plate Award event
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| Born | Linda Brown Buck January 29, 1947 Seattle, Washington, U.S. |
| Nationality | American |
| Fields | Biologist |
| Institutions |
Fred Hutchinson Cancer Research Center University of Washington, Seattle Howard Hughes Medical Institute Columbia University Harvard University |
| Alma mater |
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| Known for | Olfactory receptors |
| Notable awards |
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| Spouse | Roger Brent |
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Website www |
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Linda Brown Buck (born January 29, 1947) is an American biologist best known for her work on the olfactory system. She was awarded the 2004 Nobel Prize in Physiology or Medicine, along with Richard Axel, for their work on olfactory receptors. She is currently on the faculty of the Fred Hutchinson Cancer Research Center in Seattle.
Linda B. Buck was born in Seattle, Washington on January 29, 1947. Her father was an electrical engineer who spent his time inventing and building different items in his spare time, while her mother was a homemaker who spent a majority of her free time solving word puzzles. Buck was the second of three children, all of them being girls. Buck's parents raised them to believe that they had the ability to do anything they wanted with their lives and she attributes her affinity of science to her parents interest and dedication she grew up around. In 1994 Buck met Roger Brent, a biologist also. The two married in 2006.
Buck received her B.S. in psychology and microbiology in 1975 from the University of Washington, Seattle and her Ph.D. in immunology in 1980 from the University of Texas Southwestern Medical Center at Dallas.
In 1980, Buck began postdoctoral research at Columbia University under Dr. Richard Axel. After reading Sol Snyder's group research paper at Johns Hopkins University, Linda Buck set out to map the olfactory process at the molecular level, tracing the travel of odors through the cells of the nose to the brain. Buck and Axel worked with rat genes in their research and identified a family of genes that code for more than 1000 odor receptors and published these findings in 1991. Later that year, Buck became an assistant professor in the Neurobiology Department at Harvard Medical School where she expanded her knowledge of the nervous system and established her own lab. After finding how odors are detected by the nose, Buck published her findings in 1993 on how the inputs from different odor receptors are organized in the nose. Essentially, her primary research interest is on how pheromones and odors are detected in the nose and interpreted in the brain. She is a Full Member of the Basic Sciences Division at Fred Hutchinson Cancer Research Center, an Affiliate Professor of Physiology and Biophysics at the University of Washington, Seattle and an Investigator of the Howard Hughes Medical Institute.
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