This is a list of high school athletic conferences in the Central Region of Ohio, as defined by the OHSAA. Because the names of localities and their corresponding high schools do not always match and because there is often a possibility of ambiguity with respect to either the name of a locality or the name of a high school, the following table gives both in every case, with the locality name first, in plain type, and the high school name second in boldface type. The school's team nickname is given last.
Former members
North Division
South Division
Set to start in 2017, the league was founded by members of the Mid-Ohio Athletic Conference's Blue Division.
The league has two incarnations, the first lasting from 1927 to 1991. The second incarnation began 23 years later after travel and budget concerns brought together the ten schools that had made up league membership until 1986. The league is split into two divisions - Big School and Small School.
Big School
Small School
Former members
Conference Website: http://www.moacsports.com/MISC/home.htm
Future members
Former members
Buckeye Division
Cardinal Division
Ohio Division
Former members
Conference realigned in 2012-13.
Conference realigned again in 2016-2017. Five Divisions, Six Schools per Division, except for the Cardinal which has Seven Schools, the Ohio, Central, Cardinal, Capital, and Buckeye. The Buckeye Division, existed from 2004/05 through 2007/08 school years, was discontinued from 2008/09 through 2015/16
Buckeye Division
Capital Division
Cardinal Division
Central Division
Ohio Division
Former Members