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The Grand Orient of Belgium (French: Grand Orient de Belgique, Dutch: Grootoosten van Belgie; or G.O.B.) is a Belgian cupola of masonic lodges which is only accessible for men, and works in the basic three symbolic degrees of freemasonry.

The Grand Orient of Belgium was founded in 1833, three years after the independence of Belgium. The Grand Orient joins the Grand Orient of France and other Continental jurisdictions in not requiring initiates to believe in a Supreme Being (Great Architect of the Universe). This meant that in the 1870s the Orient broke with the United Grand Lodge of England.

During World War II, members of the Grand Orient of Belgium founded the Lodge Liberté chérie in a Nazi concentration camp and the Lodge l'Obstinée in a Nazi prisoner-of-war camp.

In 1959 five lodges of the Grand Orient of Belgium founded the Grand Lodge of Belgium in order to regain recognition by the United Grand Lodge of England which was lost in 1979. In 1989 the Grand Orient of Belgium, the Grand Lodge of Belgium, the Women's Grand Lodge Of Belgium and the Belgian Federation of Le Droit Humain signed an agreement of mutual recognition.

The GOB has often had a difficult relationship with the Roman Catholic Church (see Catholicism and Freemasonry). The Grand Orient was seen as the main source of anticlericalism during the end of the 19th century and the beginning of the 20th century.

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