Leloir Institute

The Leloir Institute is a non-profit research center in Buenos Aires specializing in biochemistry, cellular biology, molecular biology, and related activities.

The research center was inaugurated in 1947 by way of an initiative of University of Buenos Aires Physiology Professors Bernardo Houssay and Luis Leloir. The project was funded by the philanthropic support of local textile industrialist Jaime Campomar, and Dr. Houssay devoted a share of the proceeds from the Nobel Prize in Physiology he earned that year to the establishment of the institute. Initially located in a belle époque building in the Palermo section of Buenos Aires, the institute was first directed by Dr. Leloir and, following Campomar's death in 1956, it became a recipient of an endowment from both the Rockefeller Institute and the National Institutes of Health, both in the United States. The institute was formally named the Campomar Institute of Research in Biochemistry in 1958, when it was relocated to a utilitarian building belonging to the city's health ministry in the Belgrano section, nearby.

Dr. Leloir's work at the institute on nucleotides and their role in human metabolic pathways earned him the 1970 Nobel Prize in Physiology. This became known as “Leloir's pathway” and was a significant advance for biochemistry. As a consequence of this 1957 discovery, the cause of a congenital disease called galactosemia was first identified; not detected in time, it can cause mental retardation, cataracts and cirrhosis. Numerous other colleagues of his at the institute became well known in their fields, as well. These have included Enrico Cabib, Carlos Cardini, Ranwell Caputto, Alejandro Paladini, and Raúl Trucco, among others. The continued support of the Campomar Foundation allowed the institute to relocate to its current facilities in 1983.

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