"Leave Home" is a song by English big beat duo the Chemical Brothers. It was the first single released from their debut album Exit Planet Dust in 1995. It reached number 17 in the UK Singles Chart. The song contains a short sample from the Kraftwerk song "Ohm Sweet Ohm". It was used in the soundtracks to the video games SSX 3 and Wipeout 2097, and is also featured in the video game DJ Hero 2. The song was featured in the 2000 movies Gone in 60 Seconds and High Fidelity, as well as the 1997 film Dangerous Ground, the 1998 film The Acid House, the 1999 film Any Given Sunday and in episodes of The Real Hustle.

The song originally appeared on the duo's first mix album, NME Xmas Dust Up, which was produced for the NME and covermount into their Christmas 1994 issue. This was when the duo were still known as the Dust Brothers.

The recurring lyric "the brother's gonna work it out" later led to the name of their 1998 mix album of the same name.

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