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Lankenau Institute for Medical Research

Lankenau Institute
for Medical Research
Lankenau Institute for Medical Research front.jpg
Established 1927
President
and CEO
George C. Prendergast
Address 100 East Lancaster Avenue, Wynnewood, Pennsylvania 19096
484.476.8400
Website www.limr.org

Lankenau Institute for Medical Research (LIMR) is an independent, nonprofit biomedical research center located in suburban Philadelphia, U.S., on the campus of Lankenau Medical Center. LIMR specializes in basic, clinical, and translational research on cancer and cardiovascular disease. The current President and CEO of LIMR is George C. Prendergast, PhD.

LIMR’s organizational structure combines clinical and basic science research with product development in an integrated organization that includes a biotechnology company incubator. Every research group at LIMR conducts academic research that is published, but they are also required to translate their work into a marketable product or service, for development and commercialization by LIMR Development, Inc. (LDI), a subsidiary of the Institute. LIMR has coined the term "acapreneurial" to describe this unique organizational model for biomedical research, based on its combination of elements of academic science and entrepreneurial practice that are traditionally conducted apart from each other.

LIMR’s main areas of research are cancer and cardiovascular disease, although the clinical and basic researchers at LIMR also conduct investigations in diabetes, gastroenterology, pulmonology, nephrology, and public health, among others.

The main overarching theme of LIMR's basic research is modifier pathways in disease. Disease modifier pathways do not determine the onset of disease, but rather the severity of disease. In particular, LIMR scientists study general modifiers of age-associated disease that affect inflammation and immunity. For most major diseases, including most age-associated diseases, causes are often difficult to precisely define and treat. In contrast, focusing on disease severity can exert significant clinical benefits, extending health by retarding disease processes to subclinical levels. Medicines such as NSAIDs and cholesterol-lowering drugs are examples of disease-modifying medicines, illustrating the benefits that greater research into disease modifier pathways may provide.


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