Coordinates: 41°52′33″N 80°47′33″W / 41.87583°N 80.79250°W
The Lake Shore And Michigan Southern Passenger Depot is a Lake Shore and Michigan Southern Railway depot in Ashtabula, Ohio was built in 1901 to replace an older depot on the same line. The depot is located on West Thirty-second Street.
As of 2012, the depot is used as a signal house for CSX.