Kyle Seager is the eldest of three sons born to Jeff and Jody Seager. His brother Corey was selected by the Los Angeles Dodgers in the first round of the 2012 Draft, while brother Justin was selected by the Mariners in 2013.

Seager attended Northwest Cabarrus High School in Concord, North Carolina where he earned Co-North Carolina Player of the Year honors.

Seager elected to stay in-state, playing college baseball at the University of North Carolina, where he had a career .353 batting average with 17 home runs, 66 doubles and 167 RBI. In 2008, he set a school record for doubles in a season (30), was a semifinalist for the Golden Spikes Award, and was named to the watch list for both the Dick Howser Trophy and the Brooks Wallace Award.

During the summer of 2008, Seager played for the Chatham A's in the Cape Cod Baseball League.

Seager spent the majority of the 2009 season with the Class-A Clinton LumberKings. He hit .275 with a home run and 22 RBI. He also played one game with the AZL Mariners and two with the Class-A Advanced High Desert Mavericks. Seager spent the entire 2010 season with the High Desert Mavericks, batting .345 with 14 home runs and 74 RBI.

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