"Knock Me Down" is a song by the funk rock band Red Hot Chili Peppers from their fourth studio album, Mother's Milk (1989). The track, released August 22, 1989, was the album's second single and depicts a negativity towards the stereotypically egotistic lifestyle of a typical rock-star and was considered to be disavowing of drugs. "Knock Me Down" became the band's second hit, peaking at number six on the Billboard Modern Rock Tracks.

The band recorded basic tracks during March and early April 1989 at Hully Gully studios in Silver Lake. "Knock Me Down" originated during these sessions, and was formed from jam sessions without any input from returning producer Michael Beinhorn. According to Flea, the Hully Gully sessions bore fruit: "We played hard and fast more than [at] any other time in our career, I think. A lot of chops were going down [...] we played constantly, got to know each other, and came up with a record." Kiedis and Flea recognized that Frusciante's presence had become a significant influence on the band's new material as the Hully Gully sessions were proving to be extremely productive; Flea recalled that "[Frusciante] was an immense new element to the sound of our band and a big opening up for us."

"Knock Me Down" became one of the most radical shifts in style for the band. The introspective lyrics, which analyze the death of Hillel Slovak and the devastating effect drugs can have on life, were a new approach for Kiedis, who primarily wrote of sexual intercourse and a hedonistic lifestyle. The vocalist did not, however, want the track to be associated with "anti-drug" sentiments, claiming, "[the song] is about letting your friends know that you need help and then being willing to accept the help of others when you need it, whether it's from drugs or a number of other personal problems." According to music journalist Jeff Apter, the song "Knock Me Down" was "clearly the most important track the band had ever laid down; it proved that these Peppers were more than knuckleheads with socks hanging off their cocks." Musically, the track integrates the Chili Peppers' typical punk influences, but asserts heavier emphasis on melody and harmonics that lead into more alternative territory. "Knock Me Down" was originally recorded to be a duet between Kiedis and Frusciante, but the song was remixed before being released as a single; the new mix accidentally highlighted the guitarist's voice instead of Kiedis'.

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