Khubyab bin Adi was a companion of the Islamic Prophet Muhammad. He was killed during the Expedition of Al Raji. In 625 some men requested that Muhammad send instructors to teach them Islam, but the men were bribed by the two tribes of Khuzaymah who wanted revenge for the assassination of Khalid bin Sufyan by Muhammad's followers and they killed the Muslims. After killing Asim ibn Thabit, Hudhayl wanted to sell his head.
According to William Montgomery Watt, the most common version of the event states that the motives of the Banu Lahyan for attacking Muslims, was that the Banu Lahyan wanted to get revenge for the assassination of their chief at Muhammad's instigation. So they bribed the two tribes of Khuzaymah to say they wanted to convert to Islam. Watt also said that the seven men Muhammad sent may have been spies for Muhammad and instructors for Arab tribes. He also said that the it is difficult to verify the exact date the assassination of their chief took place.
According to the Muslim scholar Safiur Rahman Mubarakpuri, the Quraysh ordered Khubyab bin Adi to be crucified by Uqba bin al-Harith because he had killed Uqba bin al-Harith's father.
Muhammad ordered the The Mission of Amr bin Umayyah al-Damri to assassinate Abu Sufyan to avenge Khubyab bin Adi.