Keiskamma

Keiskamma River
Keiskammarivier
general view of Keiskammahoek where the sources of the Keiskamma River lie
Name origin: Meaning "sweet water" in the Khoekhoe language
Country	South Africa
Province	Eastern Cape Province
Tributaries
- right	Tyhume
Source	Near Keiskammahoek
- location	Amatola Mountains
- elevation	1,500 m (4,921 ft)
Mouth	Indian Ocean
- location	Near Hamburg
- elevation	0 m (0 ft)
- coordinates	33°17′0″S 27°29′20″E / 33.28333°S 27.48889°E / -33.28333; 27.48889Coordinates: 33°17′0″S 27°29′20″E / 33.28333°S 27.48889°E / -33.28333; 27.48889
Length	160 km (99 mi)
Location of the Keiskamma River mouth

The Keiskamma River (Afrikaans: Keiskammarivier) is a river in the Eastern Cape Province in South Africa. The river flows into the Indian Ocean in the Keiskamma Estuary, located by Hamburg Nature Reserve, near Hamburg, midway between East London and Port Alfred. The Keiskamma flows first in a southwestern and then in a southeastern direction after meeting its main tributary, the Tyhume River.

The Keiskamma River marked the border between the Cape Province and former British Kaffraria, known also then as Queen Adelaide's Province, until 1847.

Presently this river is part of the Mzimvubu to Keiskamma Water Management Area.

There is a small population of the endangered Eastern Province rocky (Sandelia bainsii) in the Tyhume River, part of the Keiskamma river basin.