Kay-Anlog is an upland and rural barangay of the city in Calamba, Laguna, Philippines, situated in the southern part of the city, adjacent to the barangays of Milagrosa, Makiling and Ulango.

Kay-Anlog is located at the southern edge of the city of Calamba, being one of the "upland barangays". At 224 hectares, it is one of the largest barangays by area in Calamba. It is bordered by Makiling and Milagrosa to the east, Ulango to the south, Punta to the north, Bubuyan and Burol to the west, Laurel, Batangas to the south. All of those districts are in Calamba, excluding barangay Laurel that is in Tanauan, Batangas.

Kay-Anlog is subdivided into 4 puroks (zones). These are:

The namesake of the barangay is from Anlog, a man who is the original resident of Buwisan and a former estate steward. He originally lived in Ulango, Calamba.

The phrase "Kay Anlog" means "Anlog's property". Barangay Kay-Anlog was called, spelled and recorded by the Spanish and American colonials as Barrio Quianlog.

Before 2010, Kay-Anlog was one of the barangays with the least population due to its remoteness especially from Calamba Poblacion. After the 2010 census, the population increased drastically due to government's housing projects in the barangay and became one of the most populous barangays in the city.

Kay-Anlog has a tropical climate. There is significant rainfall in most months of the year. The short dry season has little effect on the overall climate. The climate here is classified as Am by the Köppen-Geiger system. The temperature here averages 26.4 °C. The average annual rainfall is 2021 mm.

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