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Katsusaburō Yamagiwa

Yamagiwa Katsusaburō
山極 勝三郎
Yamagiwa.JPG
Yamagiwa Katsusaburō
Born (1863-02-23)23 February 1863
Ueda, Shinano Province, now Nagano Prefecture
Died 2 March 1930(1930-03-02) (aged 67)
Tokyo, Japan
Nationality Japanese
Fields Pathology
Institutions Tokyo Imperial University
Alma mater Tokyo Imperial University
Known for Chemical carcinogenesis
Notable awards Japan Academy Prize, 1919

Yamagiwa Katsusaburō (山極 勝三郎?, 23 February 1863 - 2 March 1930) was a Japanese pathologist who carried out pioneering work into the causes of cancer. He was the first to prove chemical carcinogenesis.

He was the Nobel Prize Nominee in 7 nominations.

Yamagiwa was born in Ueda, Nagano, the third son of the feudal retainer of the Ueda Domain in Shinano Province. He became the adopted son-in-law of Yoshiya Yamagiwa, a physician in Katsuya, Tokyo, and took the surname Yamagiwa. He completed his MD in 1888 from Imperial University of Tokyo. He was appointed as a professor at the Medical School, Imperial University of Tokyo and published his landmark work, Byōri Sōron Kōgi, in 1895.

Yamagiwa did all he could for the promotion of cancer research in Japan. In 1907 Cancer Science, peer-reviewed medical journal covering research in oncology, was first issued by him. In addition, he and his colleagues found the Japanese Foundation for Cancer Research in 1908.

He died in Tokyo of pneumonia in 1930 at the age of 67.

In a series of experiments conducted in 1915, Yamagiwa and his assistant Kōichi Ichikawa (1888 – 1948) induced squamous cell carcinomas on the ears of rabbits using coal tar, demonstrating the latter's carcinogenic properties.


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