Karla Maria Henriëtte Peijs (born 1 September 1944 in Tilburg) is a former Dutch politician of the CDA. She was minister of Transport and Waterworks in the second and third Balkenende cabinets. From 1 March 2007 to 1 March 2013, she was Queen's Commissioner for the province of Zeeland; she has been succeeded by Han Polman.