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Joseph DeRisi

Joseph DeRisi
Residence US
Nationality American
Fields Biology
Institutions University of California, San Francisco Howard Hughes Medical Institute
Alma mater Stanford University, University of California, Santa Cruz
Doctoral advisor Patrick O. Brown
Known for ViroChip, work on identifying SARS virus, gene expression in Plasmodium falciparum

Joseph DeRisi is an American biochemist, specializing in molecular biology, parasitology, genomics, virology, and computational biology.

He received a B.A. in Biochemistry and Molecular Biology (1992) from the University of California, Santa Cruz, and a Ph.D. in Biochemistry (1999) from Stanford University.

Joseph DeRisi is currently a Howard Hughes Medical Institute (HHMI) Investigator and a Professor and Chairman of the Department of Biochemistry and Biophysics at the University of California, San Francisco (UCSF) with a joint appointment at the California Institute for Quantitative Biosciences (QB3).

DeRisi's best-known achievements are printing the first whole genome expression array (Derisi et al., 1997, Science; PMID 9381177), performing the first broad analysis of differential gene expression in cancer cells (Derisi et al., 1996, Nature Genetics; PMID 8944026), profiling gene expression throughout the lifecycle of the malaria-causing protozoan Plasmodium falciparum, his discovery of the SARS virus, and pioneering virus discovery using gene hybridization array and DNA sequencing technologies (Wang et al., 2002, PNAS, PMID 12429852). Joe is also known for tackling any "cool problem" whatsoever, which generally come in the form of biological questions complicated by obstacles not surmountable without invention of new protocols and techniques.


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