Jonathon Pines
| Jonathon Pines | |
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Jonathan Pines in 2016, portrait via the Royal Society
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| Born | Jonathon Noë Joseph Pines October 11, 1961 |
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| Alma mater | University of Cambridge (BA, PhD) |
| Thesis | Cyclin : a major maternal message in sea urchin eggs (1987) |
| Doctoral advisor | Tim Hunt |
| Other academic advisors | Anthony R. Hunter |
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Website www |
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Jonathon Noë Joseph Pines (born 1961)FMedSciFRS is Head of the Cancer Biology Division at the Institute of Cancer Research in London. He was formerly a senior group leader at the Gurdon Institute at the University of Cambridge.
Pines was educated at the University of Cambridge where he was awarded a PhD in 1987 for research on cyclin in sea urchin eggs supervised by Tim Hunt.
Following his PhD, Pines was a postdoctoral researcher supervised by Anthony R. Hunter at the Salk Institute in La Jolla, California before moving to the Gurdon Institute at the University of Cambridge then the Institute of Cancer Research in 2015.
Pines research investigates cyclin, the cell cycle and mitosis. He pioneered the use of fluorescent tags to analyse the dynamic behavior and stability of these regulators in living cells.
Pines discoveries have revealed that mitotic regulators are targeted to specific substructures at specific times, and that mitosis is exquisitely coordinated by the destruction of key regulators at different times in cell division. Pines work has provided insights into how chromosome behavior in mitosis controls both the time and the rate at which essential mitotic regulators are destroyed, and these discoveries have wider implications for how cancers develop.
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