Sir John Willes (c. 1721 – 24 November 1784) was an English politician. He was Member of Parliament (MP) for Banbury 1746–1754, and for Aylesbury 1754–61. He lived at Astrop Park near Banbury.
He was the eldest son of John Willes, Chief Justice of the Common Pleas, and his wife Margaret Brewster; Edward Willes, judge of the Court of King's Bench, was his younger brother.