John Reid Wolfskill (September 16, 1804 - May 27, 1897) was a California pioneer who helped establish development of California's agricultural industry in the Sacramento Valley in the 19th century. In 1842, Wolfskill was the first settler to plant vineyards and fruit trees there. Born in the Bluegrass region of Kentucky and a pioneer of Solano County, "he was the first English speaking man to settle in the area around what is now Winters, California".
His brother, William Wolfskill, had migrated earlier to California and also contributed to its agricultural development. After they were settled, their younger brothers Milton, Mathus, and Sarchal Wolfskill joined John on his land grant Rancho de los Putos, later renamed as the Wolfskill Ranch. In 1935 Wolfskill's descendants donated 100 acres of the ranch to University of California, Davis for use as an experimental orchard.
Wolfskill was born near Richmond, Kentucky on September 16, 1804. He was the son of Joseph and Sarah Reid Wolfskill. His paternal grandfather, Joseph Wolfskill, was a native of Germany, who immigrated to Philadelphia, Pennsylvania. He lived in North Carolina a while, and then moved to central Kentucky. His maternal grandfather, John Reid, after whom Wolfskill was named, was a native of Ireland and immigrant to the British colonies. He was taken prisoner by the British at Charleston, South Carolina, in the American Revolutionary War. He later settled in Kentucky.
The Wolfskill family were among early migrants from Kentucky to Missouri in 1809, where they settled at Boone's Lick near the Missouri River west of St. Louis, which was developing rapidly based on the lucrative fur trade. John and his siblings grew up on the frontier.