John Otway Cuffe, 2nd Earl of Desart

John Otway Cuffe, 2nd Earl of Desart (20 February 1788 – 23 November 1820) was an Anglo-Irish politician and peer.

He was the son of Otway Cuffe, 1st Earl of Desart and Lady Anne Browne, daughter of Peter Browne, 2nd Earl of Altamont. He succeeded to his father's titles in 1804. Desart served as Member of the Parliament of the United Kingdom for Bossiney, in Cornwall, between 13 December 1808 and May 1817. He had a home at Desart Court, County Kilkenny, Ireland, and was Mayor of Kilkenny from 1809 to 1810.