John Lysaght, 1st Baron Lisle of Mountnorth in the County of Cork in the Peerage of Ireland (1702 – 15 July 1781) was an Irish peer and politician.
The eldest son of Nicholas Lysaght and Grace, daughter of Colonel Thomas Holmes of Kilmallock, County Cork, John was educated at Trinity College, Dublin. His father Nicholas was a Protestant landowner in southern Ireland, a soldier he served with William III's invading Orange army at the Battle of Boyne in 1689 as a Colonel of Horse. John's grandfather, also named John Lysaght was a Cornet in the army under Lord Inchiquin who was engaged to quell the Cathoic rising in 1641 that led to a bloody massacre in the north of protestant scots settler of the Ulster Plantation. The enusing row in the House of Commons precipitated the fall of the Earl of Strafford, and the opening conflict of English Civil War the following year.
John Lysaght sat as a Member of the Irish House of Commons for Charleville from 1727 until 1758, when on 18 September he was raised to the Peerage of Ireland as Baron Lisle, of Mountnorth in the County of Cork.
He married on 17 December 1725, Catherine Deane, third daughter and coheir of Joseph Deane, of Crumlin, a Chief Baron of the Irish Exchequer, by Margaret, sister of Henry Boyle, 1st Earl of Shannon. They had five children.
His first wife died, and in 1746 the Baron married secondly Elizabeth, only daughter of Edward Moore of Mooresfort, County Tipperary, by whom he had further issue.
He died in July 1781 and was succeeded in the barony by his son John.