Sir John Kirk, GCMG, KCB, FRS (19 December 1832 – 15 January 1922) was a Scottish physician, naturalist, companion to explorer David Livingstone, and British administrator in Zanzibar. He was born in Barry, Angus, near Arbroath, Scotland and is buried in St. Nicholas's churchyard in Sevenoaks, Kent, England. He earned his medical degree from the University of Edinburgh. He was a keen botanist throughout his life and was highly regarded by successive directors of the Royal Botanic Gardens, Kew: William Hooker, Joseph Dalton Hooker and William Turner Thiselton-Dyer.
After the death of Livingstone, Kirk pledged to continue Livingston's work to end the East African slave trade. For years he negotiated with the ruler of Zanzibar, Sultan Bargash, gaining his confidence and promising to help enrich the East African domain through legitimate commerce.
In June 1873 Kirk was acting British Consul and received simultaneous contradictory instructions from London on the Zanzibar slave trade, one to issue an ultimatum to the Sultan under threat of blockade that the slave trade should be stopped and the slave market closed, and the other not to enforce a blockade which might be taken as an act of war pushing Zanzibar towards French protection. Kirk only showed the first instruction to Barghash, who capitulated within two weeks. By 1885 the region was larger and more profitable.