John Thynne Howe (18 February 1714 – 9 May 1762) was the eldest son of John Howe, 1st Baron Chedworth.
He succeeded to the title in 1742 on the death of his father, and married 23 September 1751, Martha Parker-a-Morley-Long, daughter of Sir Philip Parker-a-Morley-Long, 3rd Baronet of Arwarton, Suffolk.
The family seat was Stowell Park, Gloucestershire, and his London residence was 25 Leicester Square. He was a breeder of thoroughbred racehorses.
There were no children from his marriage and he was succeeded in the barony by his younger brother Henry Frederick Howe, 3rd Baron Chedworth.