Sir John Godsalve (ca. 1505 – 20 November 1556), of London and Norwich, Norfolk, was an English politician.
John Godsalve was elected a Member of Parliament (MP) for Norwich in 1539 and ?1542. He was also a Clerk of the Signet.
Godsalve's first wife was Agnes Widmerpole, with whom he had two sons, William (ca. 1530–1561) and Thomas (died 1587). In 1536, Godsalve and his wife Agnes had portraits painted by Hans Holbein the Younger. Godsalve's second wife was Elizabeth White, daughter of Henry White.