John Claypole (21 August 1625 – 26 June 1688), was an officer in the Parliamentary army in 1645 during the English Civil War. He was created Lord Cleypole by Oliver Cromwell, but this title naturally came to an end with the Restoration of 1660.
Claypole married Elizabeth, Oliver Cromwell's second daughter, before October 1646, and raised a troop of horse for Parliament to oppose Charles II in 1651. He was master of the horse to his father-in-law the Lord Protector. A Member of Parliament in 1654 and 1656, he was one of Cromwell's peers in 1657. After the restoration of the monarchy he lived quietly, but may have been briefly imprisoned as a suspect in a plot in 1678, only to be released when no evidence of his involvement was presented.
Claypole was descended of a gentle family. seated at Narborough, in the county of Northampton (now known as Northborough, Cambridgeshire), upon the borders of Lincolnshire, possessing considerable estates in both those counties.
Claypole was the son of John Claypole the Elder and his wife Mary/Marie, née Angell, and the grandson of Adam Claypole. In 1637 John Claypole, senior was summoned before the Star Chamber, and the attorney-general was ordered to commence a prosecution against him for refusing to pay ship money; it cannot therefore be wondered at, that he declared for the Parliament at the start of the English Civil War in 1643, and 1644, he was appointed one "of their assessors for the county of Northampton ; but at this time he was so little known,' that his name is spelt a great variety of ways,
John Claypole snr was, probably, sheriff for his own county, as major-general William Boteler recommends him to John Thurloe, in a letter to him, dated 16 November; he was a member of Parliament in 1654 for the county of Northamptonshire; he was alive so late as 1657, when he was made a commissioner with his son, for levying the taxes upon the county of Northampton ; and to distinguish them, he is called "John Claypole, esq. senior", and his son "lord Claypole".