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Jeremy R. Knowles

Jeremy R. Knowles
Born (1935-04-28)April 28, 1935
Died April 3, 2008(2008-04-03) (aged 72)
Fields Biochemistry
Institutions Harvard University
Alma mater Oxford University
Doctoral students Hagan Bayley
Known for Enzyme catalysis

Jeremy Randall Knowles, CBE, FRS (April 28, 1935 – April 3, 2008) was a professor of chemistry at Harvard University, was Dean of the Harvard University Faculty of Arts and Sciences from 1991 to 2002. He joined Harvard in 1974, received many awards for his research, and remained at Harvard until his death, leaving the faculty for a decade to serve as Dean. Knowles died on April 3, 2008 at his home.

In 2006, he was selected by incoming interim president Derek Bok to return to his position as Dean of the Faculty of Arts and Sciences on an interim basis, replacing William C. Kirby, who was ousted by now former president Lawrence Summers.

Knowles was born in England in 1935, educated at Magdalen College School, Oxford and Balliol College, Oxford (BA 1959, DPhil 1961). He was a Pilot Officer in the Royal Air Force. During his undergraduate he did research in Richard Norman's physical organic chemistry lab. In lab, he studied the electronic effects on the rates of aromatic substitution reactions. In 1960, he became a research lecturer at Oxford. He later became Fellow and Tutor at Wadham College, Oxford. In 1961, when he took a post-doctoral fellowship at California Institute of Technology, he began working with George S. Hammond, an organic . Together, they found that some catalyzed reactions can occur up to one-million times faster than non-catalyzed reactions. Intrigued by this discovery, Knowles became an enzymologist. Knowles also was a visiting professor at Yale. in 1974, Knowles moved his research to Harvard and became a permanent professor there.


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