James Wemyss, 5th Earl of Wemyss (30 August 1699 – 21 March 1756) was the son of David Wemyss, 4th Earl of Wemyss.
On 17 September 1720, he married Janet Charteris, heiress of the great Colonel Francis Charteris, and they had four children:
In 1730, he was key to securing the release his father-in-law from Newgate Prison after he was sentenced to hang for the capital felony of rape.
His second son, Francis, the seventh Earl, legally changed his name to Charteris, his mother's maiden name, on his inheritance of Colonel Charteris's estates and fortune built upon gambling.