James Henry Robert Innes-Ker, 6th Duke of Roxburghe, KT (12 July 1816 – 23 April 1879) was a Scottish peer.
Innes-Ker was the only surviving child of the 5th Duke of Roxburghe and was educated at Eton and Christ Church, Oxford. He inherited his father's titles in 1823 and on 29 December 1836, he married Susanna Stephania Dalbiac, the only child of Sir Charles Dalbiac. They had four children:
Susanna the Dowager Duchess was one of Queen Victoria's staff until she died in 1895.