James Cecil, 3rd Earl of Salisbury, KG PC (1648 – June 1683), known as Viscount Cranborne from 1660 to 1668, was an English nobleman and politician.
Salisbury was the son of Charles Cecil, Viscount Cranborne, the son of William Cecil, 2nd Earl of Salisbury. His mother was Lady Diana Maxwell. He is said to have attended St John's College, Cambridge. In 1668 he succeeded his grandfather in the earldom. He was invested a Privy Councillor in 1679 and was made a Knight of the Garter a year later, but was expelled from the Council a few months before his death due to his participation in the Rye House Plot.
He died in June 1683 and was succeeded in his titles by his son James.
Lord Salisbury married Lady Margaret Manners, daughter of John Manners, 8th Earl of Rutland, in 1661. She bore him a son James and a daughter Lady Margaret Cecil.