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Jacob Henle

Friedrich Gustav Jakob Henle
Jakob Henle 5.jpg
Born (1809-07-09)9 July 1809
Fürth, Bavaria
Died 13 May 1885(1885-05-13) (aged 75)
Göttingen
Fields Pathology, anatomy
Alma mater University of Heidelberg
University of Bonn
Doctoral advisor Johannes Peter Müller
Known for Loop of Henle, Handbook of Systematic Human Anatomy

Friedrich Gustav Jakob Henle (9 July 1809 – 13 May 1885) was a German physician, pathologist, and anatomist. He is credited with the discovery of the loop of Henle in the kidney. His essay, "On Miasma and Contagia," was an early argument for the germ theory of disease. He was an important figure in the development of modern medicine.

Henle was born in Fürth, Bavaria, to Simon and Rachel Diesbach Henle (Hähnlein). After studying medicine at Heidelberg and at Bonn, where he took his doctor's degree in 1832, he became prosector in anatomy to Johannes Müller at Berlin. During the six years he spent in that position he published a large amount of work, including three anatomical monographs on new species of animals and papers on the structure of the lymphatic system, the distribution of epithelium in the human body, the structure and development of the hair, and the formation of mucus and pus.

In 1840, he accepted the chair of anatomy at Zürich and in 1844 he was called to Heidelberg, where he taught anatomy, physiology, and pathology. About this period he was engaged on delineating his complete system of general anatomy, which formed the sixth volume of the new edition of Samuel Thomas von Sömmering's treatise, published at Leipzig between 1841 and 1844. While at Heidelberg he published a zoological monograph on the sharks and rays, in conjunction with his master Müller, and in 1846 his famous Manual of Rational Pathology began to appear; this marked the beginning of a new era in pathological study, since in it physiology and pathology were treated, in Henle's own words, as branches of one science, and the facts of disease were systematically considered with reference to their physiological relations.


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