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J. David Gladstone Institutes

Gladstone Institutes
Established 1979
President R. Sanders Williams
Faculty 30
Staff 450
Budget $80 million
Location 1650 Owens St., San Francisco, CA, San Francisco, California, United States
Website http://gladstoneinstitutes.org/

Gladstone Institutes is an independent and nonprofit biomedical research organization whose focus is to better understand, prevent, treat and cure cardiovascular, viral and neurological conditions such as heart failure, HIV/AIDS and Alzheimer's disease. Its researchers study these diseases using techniques of basic and translational science. Another focus at Gladstone is building on the breakthrough development of induced pluripotent stem cell technology by one of its investigators, 2012 Nobel Laureate Shinya Yamanaka, to improve drug discovery, personalized medicine and tissue regeneration.

Founded in 1979, Gladstone is affiliated with the University of California, San Francisco (UCSF) and is located in San Francisco, adjacent to UCSF’s Mission Bay campus. Approximately 450 staff members—including more than 300 scientists—work at Gladstone.

Gladstone Institutes was founded in 1979 as a research and training facility housed at San Francisco General Hospital. Under the leadership of Robert Mahley—a leading cardiovascular scientist recruited from the National Institutes of Health—the institutes was launched with a $8 milliontrust from the late commercial real estate developer, J. David Gladstone.

In 1991 the institutes expanded its focus to include virology and immunology in response to the growing HIV/AIDS crisis. In 1998 it founded a third institute dedicated to studying neurological diseases.

In 2004 the Gladstone Institutes moved to a new facility on San Francisco’s Mission Bay campus. Two years later it founded a center dedicated to translating its biological discoveries into therapies. Three years later and together with Taube Philanthropies and the Koret Foundation, it founded the Taube-Koret Center for Huntington's Disease Research,.

In 2010, Dr. Mahley stepped down in order to return to active research. R. Sanders “Sandy” Williams, Dean of the School of Medicine at Duke University becoma Gladstone’s new president.


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