Isla Natividad is an island in the Pacific Ocean 6 km west off Punta Eugenia, the northwestern headland of the Mexican state of Baja California Sur. 200 meters off its northwestern end lies Roca María at 27°53′33″N 115°13′19″W / 27.89250°N 115.22194°W, with an area of 0.074 km2. Isla Natividad is separated from the mainland at Punta Eugenia by Canal de Dewey (Dewey's Channel), and from Cedros Island (Baja California), which is 15 km to the north, by Canal de Keller (Canal Kellett).
The island is part of Bahía Tortugas delegación of Mulegé municipality. It is 8.655 km2 in area. At the 2001 census, the island had a population of 384, centered in Natividad, a community of abalone, lobster, and clam fishermen, at the southeastern end (27°51′09″N 115°10′09″W / 27.85250°N 115.16917°W). Connection to the mainland is facilitated by an airstrip. There is a lighthouse in the northern part.