Isabel Charlotte Talbot, Baroness Talbot de Malahide, DBE (20 December 1851 – 22 February 1932), née Blake-Humfrey, known as Isabel Charlotte Gurney from 1873 to 1901, was an English philanthropist.
She was born at Wroxham House, Norfolk, the daughter of Robert Blake-Humfrey, a retired army officer who had lost a leg at the Battle of the Nive in 1813, and his wife Charlotte. In 1871 she married John Gurney (1845–1887), a wealthy Norwich banker from the Gurney family of Earlham Hall, connected to many social reformers. She and her husband were deeply involved in many educational and philanthropic projects in Norwich, including the conversion of Norwich Castle into the city museum. He was a Justice of the Peace and the mayor of Norwich. With his health failing, in 1886 the couple moved to Cannes, France, where he died the following year, aged 41.
She returned to their home at Sprowston Hall and lived there until 1898, when she moved to Grosvenor Place, London, and became a notable hostess. In December 1901 she married Richard Wogan Talbot, 5th Baron Talbot de Malahide (1846–1921) and moved to his home at Malahide Castle, County Dublin, where she continued her philanthropic work. During the First World War she served as president of the County of Dublin Branch of the British Red Cross Society and the Irish Joint Red Cross and St John Executive Committee. For this work she was appointed Dame Commander of the Order of the British Empire (DBE) in the 1920 civilian war honours.