"Irresistible" is a song written and recorded by the American rock band Fall Out Boy from their sixth studio album, American Beauty/American Psycho (2015). Initially released as the second promotional single from the album on January 5, 2015, it debuted at No. 77 in the US and No. 70 in the UK. In February 2015, it was released as the band's third UK single, and a music video was released on February 19.

A remix version featuring Demi Lovato, was released on October 16, 2015 and peaked at No. 48 on the Billboard Hot 100. On October 30, another remix version, featuring vocals by Migos and production by Zaytoven, was included in the remixed album Make America Psycho Again.

The song is the first track on Fall Out Boy's sixth studio album American Beauty/American Psycho, and it runs a length of three minutes and twenty seconds. The song was written by Fall Out Boy and produced by Butch Walker and Jake Sinclair. Bassist Pete Wentz compared the mood of the song to a scene in the biopic Sid and Nancy. "When I think of "Irresistible", it brings this image to my head, whether it's fictional or real, of Sid and Nancy in an alley, garbage raining down on them in an eternal spiral of romance and poison. Sometimes it's hard not to love what can hurt us the most."

The song was released as a promotional digital download online on January 5, 2015, 15 days before the album's official US release on January 20. The day of the digital release, it reached the top of the iTunes download chart, which helped it debut and peak at No. 77 on the Billboard Hot 100 chart and No. 70 on the UK Singles Chart on the strength of digital downloads. In mid-February it was released as a UK single, following "Centuries" and "American Beauty/American Psycho" in the region. In the issue dated 27 October 2015, "Irresistible" re-entered the Billboard Hot 100 chart at No. 98 following its release as a US single, with a remix featuring Demi Lovato. It has since reached No. 48 given the single release. The song was used by WWE for their Extreme Rules PPV event and it is also featured in the promotional spots for the miniseries Heroes Reborn. As of February 25, Irresistible has sold over 500,000 copies in the US.

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