"Into the Groove" is a song by American singer Madonna from the 1985 film Desperately Seeking Susan. It was featured on the re-issue of her second studio album Like a Virgin (1984) outside North America, and released on July 23, 1985, by Sire Records as the album's fourth single. The original song was included on her third greatest hits album, Celebration (2009), while remixes of it appeared on the remix compilation You Can Dance (1987), and her first greatest hits compilation The Immaculate Collection (1990). A remixed version, titled "Into the Hollywood Groove", was created by Madonna in 2003 for a Gap commercial and featured a rap by Missy Elliott.

Madonna's inspiration behind the song was the dance floor, and she wrote it while watching a handsome Puerto Rican man, across her balcony. Initially written for her friend Mark Kamins, Madonna later decided to use it as the soundtrack of her film Desperately Seeking Susan. "Into the Groove" consists of instrumentation from synthesizers and drum machines. Madonna's voice is double tracked in the chorus; the song also consists of musical contrasts, overdubs, and Madonna's voice in lower register during the bridge. The lyrics of the song are simple, written as an invitation to dance with the singer. However, it carries sexual innuendos and undertones in the meaning.

The song was appreciated by contemporary critics as well as authors, who frequently called it "Madonna's first great single". The song was a commercial success, reaching the top of the charts in Australia, Belgium, Ireland, Italy, Japan, Netherlands, New Zealand, Spain and the United Kingdom, where it was Madonna's first number-one single. In the United States, the song was only available as the B-side of the 12-inch single of "Angel", therefore it was ineligible to chart on the Billboard Hot 100 according to the rules at the time. By the end of the 1980s, "Into the Groove" was honored by Billboard magazine as the Dance Single of the Decade.

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