"Interstate Love Song" is a song by the American rock band Stone Temple Pilots. Released in 1994, the song is from the band's second studio album, Purple. Considered to be one of the band's biggest hits, "Interstate Love Song" reached number one on the Mainstream Rock Tracks chart on September 17, 1994. The song it replaced at number one was "Vasoline", also by Stone Temple Pilots. The song stayed at number one for 15 weeks, a record at the time and "Vasoline" stayed at number one for 2 weeks giving STP 17 consecutive weeks at number one with both songs combined. The song also peaked number two on the Modern Rock Tracks chart where "Vasoline" also peaked at the same position spot before. In 2003, "Interstate Love Song" was featured on the greatest hits compilation Thank You. In 2009, it was named the 58th best hard rock song of all time by VH1. The song was ranked at number 17 on Australian alternative music station Triple J's Hottest 100 countdown of 1994. In the UK, the song peaked at number 53.

Bassist Robert DeLeo brought in a song he had been working on when Stone Temple Pilots convened at Cole Rehearsal Studios in Hollywood, California in March 1992. His brother, guitarist Dean DeLeo, said, "We were in Atlanta touring Core, and Robert was playing around with the chords and the melody in a hotel room. I had a feeling about that song immediately." Robert DeLeo stated it was originally a bossa nova song when he began writing it. When he played it for singer Scott Weiland, the vocalist started humming along and turned what was originally the melody for the song's intro into a chorus melody.

Stone Temple Pilots recorded the song during sessions for Purple at the Southern Tracks studio in Atlanta, Georgia. Weiland was able to complete his vocals for the song in one take.

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