The Danube River has been a trade waterway for centuries, but with the rise of international borders and the jealousies of national states, commerce and shipping has often been hampered for narrow reasons. In addition, natural features of the river, most notably the sanding of the delta, has often hampered international trade. For these reasons, diplomats over the decades have worked to internationalize the Danube River in an attempt to allow commerce to flow as smoothly as possible.
Rivalry among the great powers — particularly Great Britain and Russia — hindered such cooperation, but in 1856, at the end of the Crimean War, and it was finally decided to establish an international organization where they all could work together on behalf of the Danube.
In 1616 an Austro-Turkish treaty was signed in Belgrade wherein the Austrians were granted the right to navigate the middle and lower Danube, at that time under the control of the Ottoman Empire. Under the 1774 Treaty of Küçük Kaynarca, ending a war between Russia and Turkey, Russia was allowed to use the lower Danube.
The Treaty of Adrianople, ending the Russo-Turkish War (1828–29), and signed on September 14, 1829, between Russia and the Ottoman Empire, provided a legal basis for excluding all foreign ships from the river delta. It gave Russia the right to establish quarantine stations on the Sulina Channel (the only one really navigable), and seven years later she made use of it. British trade began in 1834, on February 7, 1836, Russia published a decree that all Danube-bound vessels would be stopped and taken to the Russian port of Odessa for quarantine inspection.
By 1836, things had got to the point where the House of Commons debated the subject. P. Stewart told his fellows on April 20:
British enterprise has found its way to these [Danubian] provinces; and already the jealous power of Russia has assailed to obstruct its success. . . . In 1836 there will be 5,000 tons [in trade] and upwards, if Russia is pleased to permit our subjects to exercise their just and lawful right. But . . . she has already interfered, and the matter must now and immediately be brought to an issue. . . . Russia has dared to offer insult to England by laying hands upon British shipping, and demanding tribute at the mouth of the Danube. . . . there cannot be a doubt but that Russia's determination is to close up the Danube entirely, and thus to stop out growing trade with the principalities.