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Interferon gamma receptor 2

interferon gamma receptor 2 (interferon gamma transducer 1)
Identifiers
Symbol IFNGR2
Alt. symbols IFNGT1
Entrez 3460
HUGO 5440
OMIM 147569
RefSeq NM_005534
UniProt P38484
Other data
Locus Chr. 21 q22.1

Interferon gamma receptor 2 also known as IFNGR2 is a protein which in humans is encoded by the IFNGR2 gene.

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2.

Defects in IFNGR2 are a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.




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