indolepyruvate decarboxylase | |||||||||
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Identifiers | |||||||||
EC number | 4.1.1.74 | ||||||||
CAS number | 9074-92-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Search | |
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PMC | articles |
PubMed | articles |
NCBI | proteins |
In enzymology, an indolepyruvate decarboxylase (EC 4.1.1.74) is an enzyme that catalyzes the chemical reaction
Hence, this enzyme has one substrate, 3-(indol-3-yl)pyruvate, and two products, 2-(indol-3-yl)acetaldehyde and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]. Other names in common use include indol-3-yl-pyruvate carboxy-lyase, and 3-(indol-3-yl)pyruvate carboxy-lyase. This enzyme participates in tryptophan metabolism.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1OVM.