Icahn Institute for Genomics and Multiscale Biology
| Established | 2011 |
|---|---|
| Research type | Translational research |
|
Field of research
|
Systems biology, Integrative biology, Computational biology, multiscale biology |
| Director | Eric Schadt |
| Address | 1425 Madison Avenue, New York, NY 10029-6501 |
| Location | New York, NY |
| Affiliations |
Icahn School of Medicine at Mount Sinai Mount Sinai Hospital, New York |
| Website | http://icahn.mssm.edu/genomics |
The Icahn Institute for Genomics and Multiscale Biology is a biomedical and genomics research institute located in New York, NY. It is housed within the Icahn School of Medicine at Mount Sinai. Its aim is to generate and integrate many layers of biological, clinical, and environmental data in order to characterize and understand complex human diseases on a network level, and to use that data to advance information-driven medicine and to better diagnose and treat patients at Mount Sinai Hospital, New York and elsewhere.
The institute’s primary goal is to improve patient care by building predictive models to better characterize disease. These models are constructed with multiple layers of biological data, including gene expression, metabolite, DNA, and protein information, and are combined with phenotypic and clinical data, predictive modeling, and probabilistic analysis to try to elucidate the complex mechanisms of disease. This concept is called multiscale biology. To achieve this goal, scientists at the Icahn Institute for Genomics and Multiscale Biology have outfitted facilities such as the Genomics Core with new technologies to generate many types of biological information and have placed an emphasis on hiring staff with bioinformatics expertise to analyze big data. Institute director Eric Schadt has said that this approach — along with the institute’s connection to both a hospital and medical school — is expected to lead to improved and more personalized diagnoses, assessments of risk, and treatment plans for patients.
The institute was formed in 2011. Eric Schadt was named as founding director of the new institute.
The Icahn Institute for Genomics and Multiscale Biology is slated to receive more than $100 million in funding in its first several years, allocated from a $1 billion capital campaign run by Mount Sinai School of Medicine.
Originally called the Institute for Genomics and Multiscale Biology, it was renamed in 2012 when philanthropist Carl Icahn pledged $200 million to its parent organization, the Icahn School of Medicine at Mount Sinai.
In 2012, the Icahn Institute for Genomics and Multiscale Biology received certification for the first CLIA-approved next-generation sequencing lab in New York City.
Institute faculty Andrew Kasarskis, Michael Linderman, George Diaz, Ali Bashir, and Randi Zinberg taught the first class in which Mount Sinai medical students were able to fully sequence and analyze their own genomes.
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