Abd Allah ibn al-Zubayr's revolt was directed against Yazid I following the Battle of Karbala.
Ibn al-Zubayr was not active in politics during the reign of Muawiyah I, but upon the ascension of Yazid I, he refused to swear allegiance to the new caliph.
Husayn left Medina with his sisters, daughters, sons, brothers, and the sons of Hasan.
While in Mecca Abd Allah ibn al-Zubayr, Abdullah ibn Umar and Abdullah ibn Abbas advised Husayn bin Ali to make Mecca his base and fight against Yazid from Mecca. Husayn bin Ali had a lot of support in Mecca. Abd Allah ibn al-Zubayr advised Husayn bin Ali not to go to Kufa. Abd Allah ibn al-Zubayr was the grandson of Abu Bakr and the cousin of Qasim ibn Muhammad ibn Abu Bakr. Both Abd Allah ibn al-Zubayr and Qasim ibn Muhammad ibn Abu Bakr were Aisha nephews. Qasim ibn Muhammad ibn Abu Bakr was also the grandfather of Imam Jafar al-Sadiq. Husayns father Ali also had a lot of trouble with the people of Kufa and the Kharijites while he was in Kufa.