"I Ain't Mad at Cha" is a song by rapper 2Pac released shortly after his death as the sixth single from his album All Eyez on Me. It was also his last single using the stage name 2Pac. The song features contemporary soul singer Danny Boy who provided the vocals for the song's hook. The song did well in the United Kingdom, reaching the number 13 on the UK Singles Chart and on the UK R&B Charts peaking at number 3. It was not released as a single in the United States, thus making it ineligible to chart on the Billboard singles charts (due to chart rules at the time), but reached numbers 18 and 58 in the R&B and Pop Airplay charts, respectively. It also reached number two on the New Zealand Singles Chart.

The track was produced by Dat Nigga Daz (who now goes by Daz Dillinger) and samples the song "A Dream" by DeBarge. The song was recorded the same day 2Pac was released from prison, and was the second song he recorded when he came out ("Ambitionz Az a Ridah" being the first). The single was released two days after 2Pac's death. As so, by the time this single was released, 2Pac had already finished recording his next album, The Don Killuminati: The 7 Day Theory. It has been labeled by many one of the best songs on "All Eyez on Me" and one of the greatest in 2Pac's career. The song also appeared on 2Pac's Greatest Hits album. Another song on the CD single proved to be popular among fans. "Heartz of Men" appeared on 4 of 2Pac's albums, compared to 3 for "I Ain't Mad at Cha". These include: All Eyez on Me, 2Pac Live, 2Pac's Greatest Hits, and a remixed version on Nu-Mixx Klazzics. A remix was made of Rihanna's "We Ride" to include elements of "I Ain't Mad at Cha". R&B group BLACKstreet also used the identical keyboard tune in "Don't Leave Me" off of their Another Level album. The track sampled Children of the Corn's "American Dream". On the clean version there is a fourth verse, whereas on the album version there is only 3.

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