A hypoxicator is a medical device intended to provide a stimulus for the adaptation of an individual's cardiovascular system by means of breathing reduced oxygen hypoxic air and triggering mechanisms of compensation. The aim of intermittent hypoxic training or hypoxic therapy conducted with such a device is to obtain benefits in physical performance and wellbeing through improved oxygen metabolism.
There are several commercial systems available, the most popular being Hypoxico, Inc., who pioneered normobaric hypoxic altitude training systems. Most of these systems have not been cleared for medical applications by the FDA and are used by athletes for altitude training.
Advanced hypoxicators have a built-in pulse oximeter used to monitor and in some cases control the temporary reduction of arterial oxygen saturation that results in physiological responses evident at both systemic and cellular levels even after only a few minutes of hypoxia.Hypoxic Training Index (HTi) can be used to measure the delivered therapeutic dosage over the training session.
The underlying mechanisms of adaptation to mild, non-damaging, short-term (minutes) hypoxic stress (also called - intermittent hypoxic training) are complex and diverse, but are part of normal physiology and are opposite to patho-physiological effects of severe sleep apnea hypoxia.
There are a number of types of hypoxicators that can be distinguished by the method of producing hypoxic air and its delivery to the user's respiratory system. Commonly used are air separation systems employing semi-permeable membrane technology or pressure swing adsorption or (PSAS). There are also non-powered hand-held devices – rebreathers-hypoxicators.
The term hypoxicator was suggested by Russian scientists in 1985 to describe a new class of devices for Intermittent hypoxic training (IHT) – an emerging drug-free treatment for a wide range of degenerative disorders and for simulated altitude training used to achieve greater endurance performance as well as offering pre-acclimatisation for mountaineers – minimising the risk of succumbing to acute mountain sickness on a subsequent ascent.