Hyoscine butylbromide
 |
|
| Clinical data | |
|---|---|
| Trade names | Buscopan |
| Pregnancy category |
|
| Routes of administration |
By mouth, rectal, intravenous |
| ATC code | |
| Legal status | |
| Legal status |
|
| Pharmacokinetic data | |
| Bioavailability | <1% |
| Protein binding | Low |
| Biological half-life | 5 hours |
| Excretion | Renal (50%) and fecal |
| Identifiers | |
|
|
| CAS Number | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| ECHA InfoCard | 100.005.223 |
| Chemical and physical data | |
| Formula | C21H30NO4+ |
| Molar mass | 360.467 g/mol |
| 3D model (Jmol) | |
|
|
|
|
  (what is this?)
|
|
Hyoscine butylbromide, also known as scopolamine butylbromide and sold under the brandname Buscopan, is a medication used to treat crampy abdominal pain, esophageal spasms, renal colic, and bladder spasms. It is also used to improve respiratory secretions at the end of life. Hyoscine butylbromide can be taken by mouth, injection into a muscle, or into a vein.
Side effects may include sleepiness, vision changes, triggering of glaucoma, and severe allergies. Sleepiness however, is uncommon. It is unclear if it is safe in pregnancy. It is an anticholinergic agent, which does not have much effect on the brain.
It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is not available in the United States. The wholesale cost in the developing world is 0.004 to 0.11 USD per pill as of 2014. It is manufactured from hyoscine which occurs naturally in the plant deadly nightshade.
Hyoscine butylbromide is effective in treating crampy abdominal pain.
Hyoscine butylbromide is effective in reducing the duration of the first stage of labour, and it is not associated with any obvious adverse outcomes in mother or neonate.
It is also used during abdominal or pelvic MRI or CT scans to improve the quality of pictures.
...
Wikipedia