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Human chromosome 11

Chromosome 11 (human)
Human male karyotpe high resolution - Chromosome 11 cropped.png
Human chromosome 11 pair after G-banding.
One is from mother, one is from father.
Human male karyotpe high resolution - Chromosome 11.png
Chromosome 11 pair
in human male karyogram.
Features
Length (bp) 135,086,622 bp
(GRCh38)
No. of genes 1,224 (CCDS)
Type Autosome
Centromere position Submetacentric
(53.4 Mbp)
External map viewers
Ensembl Chromosome 11
Entrez Chromosome 11
NCBI Chromosome 11
UCSC Chromosome 11
Full DNA sequences
RefSeq NC_000011 (FASTA)
GenBank CM000673 (FASTA)

Chromosome 11 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome. Chromosome 11 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.

At 21.5 genes per megabase, Chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome.

More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene, and multi-gene, clusters along this chromosome.

The following are some of the gene count estimates of human chromosome 11. Because researchers use different approaches to genome annotation their predictions of the number of genes on each chromosome varies (for technical details, see gene prediction). Among various projects, the collaborative consensus coding sequence project (CCDS) takes an extremely conservative strategy. So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes.

When simply saying "number of genes", in most cases, it refers only to "number of protein-coding genes".

The following are some of the genes located on chromosome 11:

The following diseases and disorders are some of those related to genes on chromosome 11:


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