Hot cell

Shielded nuclear radiation containment chambers are commonly referred to as hot cells. The word "hot" refers to radioactivity. Hot cells are used in both the nuclear-energy and the nuclear-medicines industries. They are required to protect individuals from radioactive isotopes by providing a safe containment box in which they can control and manipulate the equipment required.

Hot cells are used to inspect spent nuclear fuel rods and to work with other items which are high-energy gamma ray emitters. For instance, the processing of medical isotopes, having been irradiated in a nuclear reactor or particle accelerator, would be carried out in a hot cell. Hot cells are of nuclear proliferation concern, as they can be used to carry out the chemical steps used to extract plutonium from reactor fuel. The cutting of the used fuel, the dissolving of the fuel and the first extraction cycle of a nuclear reprocessing PUREX process (highly active cycle) would need to be done in a hot cell. The second cycle of the PUREX process (medium active cycle) could be done in gloveboxes.

Hot cells are commonly used in the nuclear medicines industry: - for the production of radiopharmaceuticals, according to GMP guidelines (industry) - for the manipulation and dispense of radiopharmaceuticals (hospitals). The user must never be subject to shine paths that are emitted from the radioactive isotopes and therefore there generally is heavy shielding around the containment boxes, which can be made out of stainless steel 316 or other materials such as PVC or Corian. This shielding can be ensured by the use of lead (common) or materials such as concrete (very large walls are therefore required) or even tungsten. The amount of radioactivity present in the hot cell, the energy of the gamma photons emitted by the radioisotopes, and the number of neutrons that are formed by the material will prescribe how thick the shielding must be. For instance a 1 kilocurie (37 TBq) source of cobalt-60 will require thicker shielding than a 1 kilocurie (37 TBq) source of iridium-192 to give the same dose rate at the outer surface of the hot cell. Also if some actinide materials such as californium or spent nuclear fuel are used within the hot cell then a layer of water or polyethylene may be needed to lower the neutron dose rate.

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