"Hot Shots" is the sixth episode of the fifteenth season of the animated sitcom Family Guy, and the 275th episode overall. It aired on Fox in the United States on November 13, 2016, and is written by David A. Goodman and directed by John Holmquist.

When a bat invades the Griffin's home at the time when the Griffin family was watching Rational Geographic, Peter does everything he can to get rid of it. He finally succeeds when he chases the Bat who he names Bat Damon (a caricature of Matt Damon) out of Stewie's window with a tennis racket. However, he injures Stewie in the process.

They head to the Quahog Hospital so that Dr. Hartmen to heal him only for Hartman to acknowledge that Stewie has yet to receive vaccination. After they read possible bad side-effects, Peter and Lois delay the procedure. After reading more about vaccination from the internet, they decide against it. Brian objects as he mentions the potential risks, but Peter and Lois ignore him and decide to rally Quahog to ban vaccination.

Brian persuades Stewie that what they're doing is a bad idea by telling him of the horrid diseases that come with no vaccination. At the park, Peter and Lois fail to gain any support for their anti-vaccination rally even when a guy mistakes them for a person selling megaphones. At the Drunken Clam, Peter's friends see him on a commercial that promotes anti-vaccination. This leads to everyone in Quahog to not give vaccination to their child.

The next day, when Peter and Lois drop Stewie off at Quahog Preschool, they discover that no other child is there. Miss Tammy explains that there has been an outbreak of measles due to the children of Quahog not being vaccinated. Outside, they see that the authorities are forcing people to be quarantined in their houses until the measles outbreak has ended. The guy that bought the megaphone has announced the quarantine as he is being driven around in a truck. Joe Swanson interacts with a paraplegic Rhode Island State Police member and a paraplegic FBI agent until a walking crossing guard states that he has jurisdiction over them.

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