Hontenisse (population in 2002: 8,014) is a former municipality in the southwestern Netherlands, in the municipality of Hulst in the province of Zeeland. The municipality covered an area of 115.78 km² (of which 3.53 km² water).
The former municipality of Hontenisse comprised the following towns, villages and townships: Hengstdijk, Kloosterzande, Kuitaart, Lamswaarde, Ossenisse, Terhole, Vogelwaarde, Walsoorden, which are now part of Hulst. The municipality existed until 2003.
Coordinates: 51°21′05″N 4°02′29″E / 51.35139°N 4.04139°E