Honjō Shigenaga (本庄 繁長?, January 12, 1540 – January 29, 1614) was a Japanese Samurai who lived from the Azuchi–Momoyama period through to the Edo period. Shigenaga served the Uesugi clan and was known for his betrayal against them. He held the court title Echizen no kami.
Shigenaga fought at the Battle of Kawanakajima as rear left wing commander, acting as Uesugi Kenshin's retainer.
However, in 1568-1569 after the Kawanakajima campaign he briefly rebelled against Kenshin and allied himself to Takeda Shingen, Kenshin's nemesis, because Shigenaga felt dissatisfied by his small reward compared with his achievement. He first murdered Nagao Fujikage, Uesugi's vassal, and captured his castle. This betrayal forced Kenshin to lay siege to Murakami castle held by Shigenaga Honjo. The conflict proved costly for Kenshin as Irobe Katsunaga, one of his generals, was slain in the battle and could not take the castle easily. In spite of his rebellion against Kenshin, which lasted for one year, Takeda Shingen did not help him and Shigenaga was forced to surrender to Kenshin under the coordination of the Ashina clan. After the siege he was pardoned by Kenshin
After the death of Kenshin in 1578 Shigenaga supported Uesugi Kagekatsu as successor during the Siege of Ōtate. In 1588, Shigenaga once again entered conflict against the Mogami clan and Date clan wherein he defeated a Mogami army at the battle of Jugorihara (十五里ヶ原の戦い). When Mogami Yoshiaki expanding his territory into the Shōnai region in Dewa province and threatened Yoshiuji Daihoji, who sought aid from Shigenaga. Together they successfully recovered the Shōnai region as a territory of the Uesugi clan. In 1598, Uusegi Kagekatsu was transferred to Aizu Wakamatsu castle (Fukushima prefecture) by the Toyotomi government, and Shigenaga was transferred to the Aizu region.