Hereditary hyperbilirubinemia

Hereditary hyperbilirubinemia
Classification and external resources
Specialty	endocrinology
ICD-10	E80.4-E80.6
ICD-9-CM	277.4
eMedicine	med/1065 med/1066
MeSH	D006933
[]

Hereditary hyperbilirubinemia refers to the condition where levels of bilirubin are elevated, for reasons that can be attributed to a metabolic disorder.

An example is Crigler-Najjar syndrome.

UGT1A1 gene mutations causes the condition. As a result, there can be reduced functionality of the bilirubin-UGT enzyme. Eventually it causes unconjugated hyperbilirubinemia and jaundice as substance accumulates in the body due to the reduced ability of the enzyme.

...
Wikipedia